7 Steps to Strengthen Your Profitability

By Kelli Stovall, RPh, EMBA, VP of IPC Clinical Programs & Pharmacy Services; Nick Secrest, VP of IPC Member Performance Group; and Matt Tompkins, VP of IPC Marketing & Member Engagement

Updated: June 4, 2026 | Published: July 12, 2023

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Growth & Expansion

Staying profitable today isn’t easy. The financial factors that impact your margins are constantly changing. One reliable partner stands out: IPC, your trusted GPO and Secondary Wholesaler. As a member-owned cooperative, we are owned by our independent pharmacy members and led by our Board of Directors, entirely made up of owners just like you. We know you, because we are you, and we are in your corner to deliver solutions that drive profitability into your store.

In the seven steps that follow, we’ll guide you through strategies that take just 15 minutes a day to implement, so you can focus on one step at a time to build momentum toward change. Ready to take the next step toward improving your cash flow?

Let’s get started!

Alleviate Staff Shortage Impact

female pharmacist in pharmacy holding a digital tablet inspecting a pill bottle

Pharmacy has not been immune to the labor shortages that have plagued the U.S. since the Covid-19 pandemic took hold in 2020. As staff has dwindled, many pharmacists have had to fill the labor gap by spending more hours filling Rx scripts, time that could have been otherwise spent adding or expanding clinical services.

Independent pharmacies can help alleviate staff shortages by taking a strategic approach to labor analysis and workflow optimization. Start by calculating total staff costs; including wages, benefits, overtime, and technician utilization, then evaluate how pharmacists spend their time each day. Here are two worksheets to help you better understand your staffing costs and optimize workflows. Your team is your growth engine; make sure they are just as engaged in your growth as you are.

Mitigate Underwater Reimbursements

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Underwater reimbursements are an unavoidable reality for pharmacies, but they do not have to define your profitability. While we can’t eliminate them entirely, you can take decisive action to mitigate their impact. Adding profitable clinical services is one of the most effective ways you can offset underwater reimbursements and reduce reliance on shrinking dispensing margins. While you may already be providing services like vaccinations and point-of care testing, services such as pharmacogenomic (PGx) testing create new revenue opportunities while strengthening the pharmacy’s role in personalized patient care.

By leveraging solutions like ClarityX, pharmacies can identify medication therapy risks, support prescribers with actionable insights, and improve patient outcomes through optimized medication management. These high-value clinical offerings not only generate additional reimbursement opportunities but also help position the pharmacy as an essential healthcare destination within the community. Adding ClarityX (PGx) testing is a practical way to boost cash flow and reduce financial strain.

Key Statistics:

  • ClarityX tests have a profit margin ranging from 50-70%
  • These opportunities are already in front of you every day when you have patients with chronic conditions, experiencing medication switching, or excessive side effects.

Now, let’s talk dollars.

  • 10 tests per month – $1,500 – $3,500 per month in profit
  • 20 tests per month – $3000 – $7,000 per month in profit

Build Better Cash Flow through Smarter Inventory

A modern pharmacy interior with shelves fully stocked with prescription bottles,

Become familiar with your pharmacy management system’s ability to improve your turns. Many systems have inventory management built into them or work with add-on services to integrate this feature.

It’s a simple equation, really. Inventory Management = Cash Flow Management.

The correct amount of inventory you should carry can be measured by 15 inventory turns a year. If your turns are less than 12, you’re carrying too much inventory. It’s hard to pay your wholesaler bill when your cash is tied up on your shelf. This decreases your cash flow which prevents you from buying the products you need, resulting in a higher out-of-stock script volume.

It’s a delicate balance. The key is to find that ‘sweet spot’ where you don’t carry more inventory than is necessary. Less inventory equals cash in the bank. Take 15 minutes to determine your current out-of-stock and short-fill percentage.

Use Just-in-Time MedSync to Protect Cash Flow

One of the fastest ways pharmacies unintentionally create inventory problems is by tying up cash in high-cost medications that sit on the shelf. Just‑in‑Time (JIT) Medication Synchronization flips that model. Instead of carrying excess safety stock, JIT MedSync aligns ordering with confirmed patient pickup dates, so inventory arrives as close as possible to when it’s dispensed. The result is fewer out‑of‑stocks and stronger liquidity.

This approach is especially critical for high‑dollar brand medications, where pharmacies are often floating acquisition costs while waiting for reimbursement or manufacturer refunds. By confirming patient need in advance, adjudicating claims before ordering, and leveraging next‑day fulfillment through the IPC Warehouse, pharmacies dramatically shorten the window where cash is tied up in inventory. You carry what you need, when you need it, nothing more.

IPC’s Just‑in‑Time MedSync guide walks through how to operationalize this model with your team, including staff workflows, ordering guardrails, and cashflow safeguards designed specifically for today’s reimbursement environment. When paired with the IPC’s warehouse’s, next‑day delivery capabilities, JIT MedSync becomes a practical system for reducing inventory risk while keeping patients; and cash, moving on schedule.

Industry Realistic Benchmarks You Can Use

  • Average independent pharmacy inventory $150K – $300K
  • Moving from 10-12 turns to 15 turns
  • Typical reduction in on-hand inventory: 10-20%

What that means in dollars:

  • 10-20% reduction = $15K – $60K freed up cash

Conservatively, most pharmacies can unlock $15K – $60K in working capital, this isn’t “new revenue,” its cash you already earned, but had trapped on your shelf.

When you partner with IPC as your secondary wholesaler you can rely on next-day delivery and a user-friendly dashboard to streamline your ordering and avoid carrying excess inventory.

Know Your Contract, use your Available Resources to Engage help.

We know how busy you are. Chances are it feels like you’re being pulled in a thousand different directions every day. It’s human nature to then scramble to solve problems without a grounded plan or approach. We hear about this frustration a lot when it comes to purchasing. Bouncing from website to website to find the very best deal.

You might find a short-term deal at the expense of losing thousands of dollars in rebates by not staying compliant with your primary wholesaler. You don’t have time to learn the nuances of your primary wholesaler contract to fully maximize it.

You can’t do it alone. You need help.

Master Your GCR: Strategies to Maintain It This Month

Pharmacist seated at a desk reviewing a computer dashboard displaying pharmacy purchasing and rebate analytics, including charts on spending, rebate percentages, and savings breakdown, in a clean clinical office setting with shelves of medications in the background.

To keep your cost of inventory at a minimum, it is critically important to satisfy your generic compliance ratio (GCR) set forth in your primary wholesaler agreement. The rebates you earn by hitting your target GCR every month can be game-changing, putting cash back in your pharmacy.

Many pharmacy owners tell us that their number one challenge is to reduce the costs, specifically the cost of goods. At IPC, our goal is to help you enhance your profitability and help you create a purchasing strategy that can directly impact your bottom line in a positive way.

This can be done using our 4-step process:

  1. Analyze your Existing Wholesale Agreement: Identify potential opportunity in your agreement structure, write it down, and explore the path to taking advantage of that opportunity. Take time with your GPO representative to break down the components of your prime vendor agreement to know how your purchases affect your rebates.
    Do some brands not qualify for standard WAC minus pricing? Does your rebate percentage fluctuate based on your purchase volume?
  1. Break down Brand & Generic costs per item: Be confident you know what your final price is. You might know what the best price could be, but until you break it down, you cannot be certain you are paying the best price.
    Select a commonly disbursed brand, determine from your agreement the amount of rebates to be received and apply based on previous month’s numbers to identify the potential or actual net price.

    * Know your top 5 brand items and see if you can improve the price

  1. Identify & Utilize Available Tools: Determine if you have access to tools available to track your costs and manage them. Make sure your vendor ordering system and pharmacy management system have the final cost components displayed.
  1. Develop Ongoing Purchasing Strategies: Involve your team members in the strategy to ensure they are following through with the strategies and make sure the path is clear in moving toward a common goal.

Join the Fight for Independent Pharmacy Reform

Pharmacy professional seated at a desk using a laptop displaying a legislative action center webpage with a contact form to reach a representative, surrounded by a clean office setting with a phone, notebook, and pharmacy-related materials.

This is the ONE step in this blog that requires a long-term solution. In early 2026 Congress passed the first meaningful PBM reforms in more than 20 years. These reforms included:

  • Requirements for CMS to define and enforce “reasonable & relevant” Medicare Part D contract terms.
  • Allow CMS to track payment trends & pharmacy participation in PBM networks.
  • Create new designation for “essential retail pharmacies” encouraging the recognition for the role community pharmacies play in patient care access.
  • Prohibit PBM compensation from being tied to a drug’s manufacturer price list.
  • Requires all private sector self-funded PBM contracts, including ERISA & Labor plans to pass through rebates, mandatory reporting, health plan notice requirements and imposes penalties for violations

While this is a win for pharmacy, the fight is far from over. Additional legislative efforts are ongoing and need your help. Here are some of our top priorities:

  • Passage of “The Equitable Community Access to Pharmacists Act” ECAPS
  • Medicaid Managed Prescription Program Reform
  • PBM Vertical Integration Divestiture Legislation

This runaway train needs to be stopped but we can’t do it alone. This initiative requires strength in numbers. Here’s how you can take action today:

  • Join groups like NCPA or your state pharmacy association to fight the good fight.
  • Participate in Voter Voice campaigns to contact your legislators directly. Act quickly to ensure they understand how these decisions impact independent pharmacies.
  • Take 15 minutes to connect with our team here and visit the IPC Legislative Action Center to contact your legislator directly.

 

IPC is committed to driving critical legislative reforms on your behalf, focusing on top issues like 340B Reform, Federal Part D PBM Reform, Medicaid Managed Care Reform and Pharmacy Provider Status.

Our Government Relations team has been fighting for independent pharmacy for decades. In just the past three years, we’ve engaged with legislators in more than 16 states in support and passage of more than 30 laws involving pro-independent pharmacy legislation.

These wins are significant, but the fight is far from over. What we need from you as a representative of independent pharmacy is to reach out to your elected officials when we ask and download your Legislative Tool Kit to engage with your legislators at the state and federal level.

Leverage Available Tools to Hit Your GCR Mark

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As emphasized in Step #5, hitting and maintaining your GCR each month is essential for your bottom line, potentially saving you thousands of dollars. IPC partners with trusted vendors who can automate and simplify GCR management, ensuring you maximize earnings. Here’s how:

SureCost: Streamline Compliance and Maximize Savings

Rx Assassins: Real-Time Compliance and Savings Management

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CheckmyRxCost: AI-Powered Procurement Optimization

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Pharmacy Marketplace: AI-Driven Purchasing Recommendations

Pharmacy Marketplace analyzes your pharmacy’s unique dispensing habits to recommend the best deals without compromising compliance.

Key Benefits:

Bonus: IPC Digital Health is Building the Digital Ecosystem for Independent Pharmacies

IPC Digital Health - Future-Proofing Independent Pharmacy

Your independent pharmacy is evolving into a modern healthcare access point, and digital services are an essential part of that transformation. IPC has partnered with innovative technologies to help connect patients to care, prescription savings and delivery keeping you at the center of care.

Today IPC Digital Health offers:

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In Conclusion

When you step back and look at the full picture, the opportunities in front of you are significant. Unlocking working capital through inventory management, adding and enhancing clinical services and creating capacity for those services through smarter staffing; you can find anywhere from $60K – $150K in financial impact within your control.

None of this happens all at once; the goal isn’t to implement everything overnight, it’s to take one focused step at a time. Spend 15 minutes, make one improvement, and build momentum from there. That’s how meaningful, sustainable profitability is created and IPC is here to help you every step of the way.